HMG

🔹 What is HMG?

Class: Glycoprotein hormone preparation containing FSH (follicle-stimulating hormone) and LH (luteinizing hormone), derived from the urine of postmenopausal women. Mechanism:

• FSH: Stimulates follicular development in women; supports spermatogenesis in men.
• LH: Stimulates testosterone production in men; supports ovulation in women.
• Used clinically in fertility treatments and sometimes in combination with HCG for hormonal support.

Primary focus:

• Women: Ovulation induction and fertility support.
• Men: Spermatogenesis and endogenous testosterone support.

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🔹 Oral Dosage: Not used; degraded in GI tract. Only injectable effective.

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🔹 Injectable / Subcutaneous Dosage: Women: 75–150 IU daily for 5–12 days (IVF or ovulation induction). Men: 75–150 IU 2–3 times per week for 3–6 months (often stacked with HCG). Rationale: Subcutaneous or intramuscular injection provides consistent FSH and LH delivery.

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🔹 Cycle Length:

• Women: 5–12 days per cycle (depending on follicular development).
• Men: 3–6 months for spermatogenesis, often with HCG.

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🔹 Optimal Dosing Window:

• Daily injections at consistent times, typically morning.

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✅ Educational Integration Example: Men: HMG 75 IU 2–3x/week + HCG 500 IU 2–3x/week for 3–6 months. Women: HMG 75 IU daily for 7–10 days with HCG trigger for ovulation.

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🔹 Stacking Strategy (Educational / Complementary): Men: HCG to maintain testosterone, antioxidants (CoQ10, NAC, Vitamins C/E) for sperm quality. Women: HCG as ovulation trigger, optional FSH analogues, antioxidants for oocyte quality.

Disclaimer: Do not rely on any dosing information provided, this is for educational and research only. Always double and triple check alternative references for education. Please consult with healthcare provider for your specific dosing and protocol if applicable.